Description
Product Characteristics:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.
Subcellular location: Nucleus
Synonyms: BRIX, Brix domain containing 2, Brix domain containing protein 2, BRIX1, BRX1, biogenesis of ribosomes, homolog S. cerevisiae, FLJ11100, Ribosome biogenesis protein Brix, BRX1_HUMAN.
Target Information: Required for biogenesis of the 60S ribosomal subunit (By similarity)